Altered Plasma Profile of Antioxidant Proteins as an Early Correlate of Pancreatic β Cell Dysfunction

Por Kuo, Taiyi, Kim-Muller, Ja Young, McGraw, Timothy E., Accili, Domenico
Publicado no J Biol Chem (2016)

Increased Atherosclerosis and Endothelial Dysfunction in Mice Bearing Constitutively Deacetylated Alleles of Foxo1 Gene

Por Qiang, Li, Tsuchiya, Kyoichiro, Kim-Muller, Ja-Young, Lin, Hua V., Welch, Carrie, Accili, Domenico
Publicado em 2012

Proatherogenic Abnormalities Of Lipid Metabolism In SirT1 Transgenic Mice Are Mediated Through Creb Deacetylation

Por Qiang, Li, Lin, Hua V., Kim-Muller, Ja Young, Welch, Carrie L., Gu, Wei, Accili, Domenico
Publicado em 2011

Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnlβ (RELMβ) Null Mice: A Model of Intestinal Immune System Dysfunction in Disease Suscepti...

Por Wernstedt Asterholm, Ingrid, Kim-Muller, Ja Young, Rutkowski, Joseph M., Crewe, Clair, Tao, Caroline, Scherer, Philipp E.
Publicado no Am J Pathol (2016)

FoxO1 Deacetylation Decreases Fatty Acid Oxidation in β-Cells and Sustains Insulin Secretion in Diabetes

Por Kim-Muller, Ja Young, Kim, Young Jung R., Fan, Jason, Zhao, Shangang, Banks, Alexander S., Prentki, Marc, Accili, Domenico
Publicado no J Biol Chem (2016)

Aldehyde dehydrogenase 1a3 defines a subset of failing pancreatic β cells in diabetic mice

Por Kim-Muller, Ja Young, Fan, Jason, Kim, Young Jung R., Lee, Seung-Ah, Ishida, Emi, Blaner, William S., Accili, Domenico
Publicado no Nat Commun (2016)

When β-Cells Fail: Lessons from Dedifferentiation

Por Accili, Domenico, Talchai, Shivatra Chutima, Kim-Muller, JaYoung, Cinti, Francesca, Ordelheide, Anna Maria, Kuo, Taiyi, Fan, Jason, Son, Jinsook
Publicado no Diabetes Obes Metab (2016)

Blunted Refeeding Response and Increased Locomotor Activity in Mice Lacking FoxO1 in Synapsin-Cre–Expressing Neurons

Por Ren, Hongxia, Plum-Morschel, Leona, Gutierrez-Juarez, Roger, Lu, Taylor Y., Kim-Muller, Ja Young, Heinrich, Garrett, Wardlaw, Sharon L., Silver, Rae, Accili, Domenico
Publicado em 2013

Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes

Por Cinti, Francesca, Bouchi, Ryotaro, Kim-Muller, Ja Young, Ohmura, Yoshiaki, Sandoval, P. R., Masini, Matilde, Marselli, Lorella, Suleiman, Mara, Ratner, Lloyd E., Marchetti, Piero, Accili, Domenico
Publicado no J Clin Endocrinol Metab (2016)

Metabolic Inflexibility Impairs Insulin Secretion And Results In MODY-like Diabetes In Triple FoxO-deficient Mice

Por Kim-Muller, Ja Young, Zhao, Shangang, Srivastava, Shekhar, Mugabo, Yves, Noh, Hye-Lim, Kim, YoungJung R., Madiraju, S.R. Murthy, Ferrante, Anthony W., Skolnik, Edward Y., Prentki, Marc, Accili, Domenico
Publicado em 2014

Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knock-in of acetylation-defective alleles in mice

Por Banks, Alexander S., Kim-Muller, Ja Young, Mastracci, Teresa L., Kofler, Natalie M., Qiang, Li, Haeusler, Rebecca A., Jurczak, Michael J., Laznik, Dina, Heinrich, Garrett, Samuel, Varman T., Shulman, Gerald I., Papaioannou, Virginia E., Accili, Domenico
Publicado em 2011