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IL-2 Controls Trafficking Receptor Gene Expression and Th2 Response for Skin and Lung Inflammation
Both Il2(−/−) mice and Scurfy (Sf) mutant mice that are deficient in FoxP3, develop multi-organ inflammation but only the latter display severe skin and lung inflammation. In contrast, Sf.Il2(−/−) double mutant mice do not display skin inflammation and markedly reduced lung inflammation. In this rev...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3444569/ https://ncbi.nlm.nih.gov/pubmed/22940635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2012.07.015 |
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