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IL-2 Controls Trafficking Receptor Gene Expression and Th2 Response for Skin and Lung Inflammation

Both Il2(−/−) mice and Scurfy (Sf) mutant mice that are deficient in FoxP3, develop multi-organ inflammation but only the latter display severe skin and lung inflammation. In contrast, Sf.Il2(−/−) double mutant mice do not display skin inflammation and markedly reduced lung inflammation. In this rev...

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Autors principals: Ju, Shyr-Te, Sharma, Rahul, Gaskin, Felicia, Fu, Shu Man
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444569/
https://ncbi.nlm.nih.gov/pubmed/22940635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2012.07.015
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