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A Novel Function of IL-2: Chemokine/Chemoattractant/Retention Receptor Genes Induction in Th Subsets for Skin and Lung Inflammation

The Foxp3(+)CD4(+) regulatory T-cell (Treg)-deficient Scurfy (Sf) mice rapidly develop severe inflammation in the skin and lungs with expanded Th subsets bearing increased expression of various chemokine/chemoattractant/retention receptor genes (CRG). Nine different double mutants were generated to...

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Detalhes bibliográficos
Main Authors: Sharma, Rahul, Sung, Sun-Sang J., Gaskin, Felicia, Fu, Shu Man, Ju, Shyr-Te
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358580/
https://ncbi.nlm.nih.gov/pubmed/22464450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2012.02.001
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