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A Novel Function of IL-2: Chemokine/Chemoattractant/Retention Receptor Genes Induction in Th Subsets for Skin and Lung Inflammation
The Foxp3(+)CD4(+) regulatory T-cell (Treg)-deficient Scurfy (Sf) mice rapidly develop severe inflammation in the skin and lungs with expanded Th subsets bearing increased expression of various chemokine/chemoattractant/retention receptor genes (CRG). Nine different double mutants were generated to...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358580/ https://ncbi.nlm.nih.gov/pubmed/22464450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2012.02.001 |
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