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IL-2: A Two-Faced Master Regulator of Autoimmunity

CD4(+) T-cell (Th) cytokines provide important regulatory and effector functions of T-cells. Among them, IL-2 plays a unique role. IL-2 is required for the generation and maintenance of regulatory T-cells (Treg) to provide lifelong protection from autoimmune disease. Whether IL-2 is also required fo...

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Bibliographic Details
Main Authors: Sharma, Rahul, Fu, Shu Man, Ju, Shyr-Te
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046218/
https://ncbi.nlm.nih.gov/pubmed/21282039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2011.01.001
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