Perlecan Domain V Induces VEGf Secretion in Brain Endothelial Cells through Integrin α(5)β(1) and ERK-Dependent Signaling Pathways

Perlecan Domain V (DV) promotes brain angiogenesis by inducing VEGF release from brain endothelial cells (BECs) following stroke. In this study, we define the specific mechanism of DV interaction with the α(5)β(1) integrin, identify the downstream signal transduction pathway, and further investigate...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Clarke, Douglas N., Al Ahmad, Abraham, Lee, Boyeon, Parham, Christi, Auckland, Lisa, Fertala, Andrezj, Kahle, Michael, Shaw, Courtney S., Roberts, Jill, Bix, Gregory J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2012
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444475/
https://ncbi.nlm.nih.gov/pubmed/23028886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045257
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