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Endostatin binds nerve growth factor and thereby inhibits neurite outgrowth and neuronal migration in-vitro

Endostatin (ES), the C-terminal fragment of collagen XVIII known for its anti-angiogenic properties, is associated with neurological diseases in mammals. In this study, we investigated the effect of ES on nerve growth factor (NGF)-induced neuronal differentiation, migration, neuritogenesis, and neur...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Ahmad, Abraham Al, Lee, Boyeon, Stack, Jonathan, Parham, Christi, Campbell, Joel, Clarke, Douglas, Fertala, Andrzej, Bix, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246509/
https://ncbi.nlm.nih.gov/pubmed/20846515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.09.023
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