Perlecan Domain V Therapy for Stroke: A Beacon of Hope?

Por Bix, Gregory J
Publicado em 2012

Oxygen-Glucose Deprivation (OGD) and Interleukin-1 (IL-1) Differentially Modulate Cathepsin B/L Mediated Generation of Neuroprotective Perlecan LG3 by Neurons

Por SAINI, MAXIM G, BIX, GREGORY J
Publicado em 2011

Successfully Climbing the “STAIRs”: Surmounting Failed Translation of Experimental Ischemic Stroke Treatments

Por Kahle, Michael P., Bix, Gregory J.
Publicado em 2012

Perlecan and the Blood-Brain Barrier: Beneficial Proteolysis?

Por Roberts, Jill, Kahle, Michael P., Bix, Gregory J.
Publicado em 2012

Mice deficient in endothelial α5 integrin are profoundly resistant to experimental ischemic stroke

Por Roberts, Jill, de Hoog, Leon, Bix, Gregory J
Publicado no J Cereb Blood Flow Metab (2015)

Perlecan Domain V Is Neuroprotective and Affords Functional Improvement in a Photothrombotic Stroke Model in Young and Aged Mice

Por Bix, Gregory J., Gowing, Emma K., Clarkson, Andrew N.
Publicado em 2013

Oxygen-Glucose Deprivation (OGD) and Interleukin-1α (IL-1α) Trigger the Release of Perlecan LG3 by Cells of Neurovascular Unit (NVU)

Por Saini, Maxim G., Pinteaux, Emmanuel, Lee, Boyeon, Bix, Gregory J
Publicado em 2011

Effects of histidine-rich glycoprotein on cerebral blood vessels

Por Steelman, Samantha M, Hein, Travis W, Gorman, Amy, Bix, Gregory J
Publicado em 2013

Stroke neuroprotection revisited: Intra-arterial verapamil is profoundly neuroprotective in experimental acute ischemic stroke

Por Maniskas, Michael E, Roberts, Jill M, Aron, Ishi, Fraser, Justin F, Bix, Gregory J
Publicado no J Cereb Blood Flow Metab (2015)

Juvenile traumatic brain injury induces long-term perivascular matrix changes alongside amyloid-beta accumulation

Por Jullienne, Amandine, Roberts, Jill M, Pop, Viorela, Paul Murphy, M, Head, Elizabeth, Bix, Gregory J, Badaut, Jérôme
Publicado no J Cereb Blood Flow Metab (2014)

Endostatin binds nerve growth factor and thereby inhibits neurite outgrowth and neuronal migration in-vitro

Por Ahmad, Abraham Al, Lee, Boyeon, Stack, Jonathan, Parham, Christi, Campbell, Joel, Clarke, Douglas, Fertala, Andrzej, Bix, Gregory J.
Publicado no Brain Res (2010)

Perlecan Domain V Induces VEGf Secretion in Brain Endothelial Cells through Integrin α(5)β(1) and ERK-Dependent Signaling Pathways

Por Clarke, Douglas N., Al Ahmad, Abraham, Lee, Boyeon, Parham, Christi, Auckland, Lisa, Fertala, Andrezj, Kahle, Michael, Shaw, Courtney S., Roberts, Jill, Bix, Gregory J.
Publicado em 2012

Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents

Por Lee, Boyeon, Clarke, Douglas, Al Ahmad, Abraham, Kahle, Michael, Parham, Christi, Auckland, Lisa, Shaw, Courtney, Fidanboylu, Mehmet, Orr, Anthony Wayne, Ogunshola, Omolara, Fertala, Andrzej, Thomas, Sarah A., Bix, Gregory J.
Publicado em 2011

Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents

Por Lee, Boyeon, Clarke, Douglas, Al Ahmad, Abraham, Kahle, Michael, Parham, Christi, Auckland, Lisa, Shaw, Courtney, Fidanboylu, Mehmet, Orr, Anthony Wayne, Ogunshola, Omolara, Fertala, Andrzej, Thomas, Sarah A., Bix, Gregory J.
Publicado em 2012

Perlecan Domain V is Upregulated in Human Brain Arteriovenous Malformation (BAVM) and could Mediate VEGF Effect in Lesional Tissue

Por Kahle, Michael P., Lee, Boyeon, Pourmohamad, Tony, Cunningham, Austin, Su, Hua, Kim, Helen, Chen, Yongmei, McCulloch, Charles E., Barbaro, Nicholas M., Lawton, Michael T., Young, William L., Bix, Gregory J.
Publicado em 2012