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Perlecan Domain V Is Neuroprotective and Affords Functional Improvement in a Photothrombotic Stroke Model in Young and Aged Mice

With the failure of so many pre-clinical stroke studies to translate into the clinic, there is a need to find new therapeutics to minimize the extent of cellular damage and aid in functional recovery. Domain V (DV), the c-terminal protein fragment of the vascular basement membrane component, perleca...

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Autors principals: Bix, Gregory J., Gowing, Emma K., Clarkson, Andrew N.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937769/
https://ncbi.nlm.nih.gov/pubmed/24323378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-013-0266-1
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