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Perlecan Domain V Inhibits Amyloid-β Induced Brain Endothelial Cell Toxicity and Restores Angiogenic Function
In Alzheimer’s disease (AD), amyloid-β (Aβ) deposits in the cerebrovasculature can result in neurovascular dysfunction and/or cerebral amyloid angiopathy. The accumulation of Aβ in blood vessels can cause endothelial cell damage, resulting in impaired Aβ clearance by the blood-brain barrier. Additio...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3996518/ https://ncbi.nlm.nih.gov/pubmed/23979025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-130683 |
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