Perlecan and the Blood-Brain Barrier: Beneficial Proteolysis?

The cerebral microvasculature is important for maintaining brain homeostasis. This is achieved via the blood-brain barrier (BBB), composed of endothelial cells with specialized tight junctions, astrocytes, and a basement membrane (BM). Prominent components of the BM extracellular matrix (ECM) includ...

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Autores principales: Roberts, Jill, Kahle, Michael P., Bix, Gregory J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425914/
https://ncbi.nlm.nih.gov/pubmed/22936915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00155
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