Perlecan regulates pericyte dynamics in the maintenance and repair of the blood–brain barrier

Ischemic stroke causes blood–brain barrier (BBB) breakdown due to significant damage to the integrity of BBB components. Recent studies have highlighted the importance of pericytes in the repair process of BBB functions triggered by PDGFRβ up-regulation. Here, we show that perlecan, a major heparan...

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Библиографические подробности
Опубликовано в: :J Cell Biol
Главные авторы: Nakamura, Kuniyuki, Ikeuchi, Tomoko, Nara, Kazuki, Rhodes, Craig S., Zhang, Peipei, Chiba, Yuta, Kazuno, Saiko, Miura, Yoshiki, Ago, Tetsuro, Arikawa-Hirasawa, Eri, Mukouyama, Yoh-suke, Yamada, Yoshihiko
Формат: Artigo
Язык:Inglês
Опубликовано: Rockefeller University Press 2019
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781430/
https://ncbi.nlm.nih.gov/pubmed/31541017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807178
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