Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation

Perlecan (Hspg2) is a heparan sulfate proteoglycan expressed in basement membranes and cartilage. Perlecan deficiency (Hspg2(−/−)) in mice and humans causes lethal chondrodysplasia, which indicates that perlecan is essential for cartilage development. However, the function of perlecan in endochondra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ishijima, Muneaki, Suzuki, Nobuharu, Hozumi, Kentaro, Matsunobu, Tomoya, Kosaki, Keisuke, Kaneko, Haruka, Hassell, John R., Arikawa-Hirasawa, Eri, Yamada, Yoshihiko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340529/
https://ncbi.nlm.nih.gov/pubmed/22421594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2012.02.006
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