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Perlecan Facilitates Neuronal Nitric Oxide Synthase Delocalization in Denervation-Induced Muscle Atrophy

Perlecan is an extracellular matrix molecule anchored to the sarcolemma by a dystrophin–glycoprotein complex. Perlecan-deficient mice are tolerant to muscle atrophy, suggesting that perlecan negatively regulates mechanical stress-dependent skeletal muscle mass. Delocalization of neuronal nitric oxid...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Nakada, Satoshi, Yamashita, Yuri, Machida, Shuichi, Miyagoe-Suzuki, Yuko, Arikawa-Hirasawa, Eri
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700382/
https://ncbi.nlm.nih.gov/pubmed/33238404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112524
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