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Perlecan deficiency causes endothelial dysfunction by reducing the expression of endothelial nitric oxide synthase

Perlecan is a major heparan sulfate proteoglycan found in the subendothelial extracellular matrix of the vascular wall. The aim of this study was to investigate the role of perlecan in the regulation of vascular tone. A previously developed conditional perlecan‐deficient mouse model was used to meas...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Physiol Rep
Päätekijät: Nonaka, Risa, Iesaki, Takafumi, de Vega, Susana, Daida, Hiroyuki, Okada, Takao, Sasaki, Takako, Arikawa‐Hirasawa, Eri
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Wiley Periodicals, Inc. 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387761/
https://ncbi.nlm.nih.gov/pubmed/25626871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12272
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