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Perlecan deficiency causes endothelial dysfunction by reducing the expression of endothelial nitric oxide synthase
Perlecan is a major heparan sulfate proteoglycan found in the subendothelial extracellular matrix of the vascular wall. The aim of this study was to investigate the role of perlecan in the regulation of vascular tone. A previously developed conditional perlecan‐deficient mouse model was used to meas...
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| Pubblicato in: | Physiol Rep |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley Periodicals, Inc.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4387761/ https://ncbi.nlm.nih.gov/pubmed/25626871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12272 |
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