Perlecan regulates pericyte dynamics in the maintenance and repair of the blood–brain barrier

Ischemic stroke causes blood–brain barrier (BBB) breakdown due to significant damage to the integrity of BBB components. Recent studies have highlighted the importance of pericytes in the repair process of BBB functions triggered by PDGFRβ up-regulation. Here, we show that perlecan, a major heparan...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Nakamura, Kuniyuki, Ikeuchi, Tomoko, Nara, Kazuki, Rhodes, Craig S., Zhang, Peipei, Chiba, Yuta, Kazuno, Saiko, Miura, Yoshiki, Ago, Tetsuro, Arikawa-Hirasawa, Eri, Mukouyama, Yoh-suke, Yamada, Yoshihiko
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781430/
https://ncbi.nlm.nih.gov/pubmed/31541017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807178
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