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SPHINGOSINE KINASE TYPE 2 INHIBITION ELEVATES CIRCULATING SPHINGOSINE 1-PHOSPHATE

Sphingosine 1-phosphate (S1P) is a pleiotropic lipid mediator involved in numerous cellular and physiological functions. Notable among these are cell survival and migration as well as lymphocyte trafficking. S1P, which exerts its effects via five G protein coupled receptors (S1P1-5), is formed by th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kharel, Yugesh, Raje, Mithun, Gao, Ming, Gellett, Amanda M., Tomsig, Jose L., Lynch, Kevin R., Santos, Webster L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443596/
https://ncbi.nlm.nih.gov/pubmed/22747486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120609
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