Metabolic manifestations of insulin deficiency do not occur without glucagon action

To determine unambiguously if suppression of glucagon action will eliminate manifestations of diabetes, we expressed glucagon receptors in livers of glucagon receptor-null (GcgR(−/−)) mice before and after β-cell destruction by high-dose streptozotocin. Wild type (WT) mice developed fatal diabetic k...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Lee, Young, Berglund, Eric D., Wang, May-yun, Fu, Xiaorong, Yu, Xinxin, Charron, Maureen J., Burgess, Shawn C., Unger, Roger H.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443167/
https://ncbi.nlm.nih.gov/pubmed/22891336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205983109
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares