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Metabolic manifestations of insulin deficiency do not occur without glucagon action
To determine unambiguously if suppression of glucagon action will eliminate manifestations of diabetes, we expressed glucagon receptors in livers of glucagon receptor-null (GcgR(−/−)) mice before and after β-cell destruction by high-dose streptozotocin. Wild type (WT) mice developed fatal diabetic k...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443167/ https://ncbi.nlm.nih.gov/pubmed/22891336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205983109 |
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