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R-loops and genomic instability in Bre1 (RNF20/40)-deficient cells

We have proposed that maintenance of genomic stability may constitute the basis for the tumor-suppressing activity of the Bre1 (RNF20/RNF40) complex. Revisiting the evidence we presented in our recent publication, we discuss the mechanism by which maintenance of genomic stability by the Bre1 complex...

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Autores principales: Chernikova, Sophia B., Brown, J. Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442907/
https://ncbi.nlm.nih.gov/pubmed/22825248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21090
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