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R-loops cause replication impairment and genome instability during meiosis
R-loops are harmful structures with a negative impact on transcription and recombination during mitosis, but no information exists for meiosis. We used Saccharomyces cerevisiae and Caenorhabditis elegans THO mutants as a tool to determine the consequences of R-loops in meiosis. We found that both S....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463965/ https://ncbi.nlm.nih.gov/pubmed/22878416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.119 |
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