Relationship of Ketamine’s Plasma Metabolites with Response, Diagnosis, and Side Effects in Major Depression

BACKGROUND: Ketamine has rapid antidepressant effects lasting as long as 1 week in patients with major depressive disorder (MDD) and bipolar depression (BD). Ketamine is extensively metabolized. This study examined the relationship between ketamine metabolites and response, diagnosis, and psychotomi...

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Detalhes bibliográficos
Main Authors: Zarate, Carlos A., Brutsche, Nancy, Laje, Gonzalo, Luckenbaugh, David A., Vattem Venkata, Swarajya L., Ramamoorthy, Anuradha, Moaddel, Ruin, Wainer, Irving W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442255/
https://ncbi.nlm.nih.gov/pubmed/22516044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.03.004
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