Role of Gab1 in UV-Induced c-Jun NH(2)-Terminal Kinase Activation and Cell Apoptosis

Exposure of mammalian cells to UV irradiation leads to activation of the c-Jun NH(2)-terminal protein kinase (JNK) pathway, which is associated with cell apoptosis. However, the molecular mechanism for JNK activation by UV exposure is not fully understood. We show here an essential role of a multisu...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Sun, Yingqing, Yuan, Jing, Liu, Houqi, Shi, Zhongqing, Baker, Kelly, Vuori, Kristiina, Wu, Jie, Feng, Gen-Sheng
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2004
Subjects:	Cell Growth and Development
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14749370/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.4.1531-1539.2004
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