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Pseudomonas aeruginosa ExoT Acts In Vivo as a GTPase-Activating Protein for RhoA, Rac1, and Cdc42

The Pseudomonas aeruginosa protein ExoT is a bacterial GTPase-activating protein (GAP) that has in vitro activity toward Rho, Rac, and Cdc42 GTPases. Expression of ExoT both inhibits the internalization of strain PA103 by macrophages and epithelial cells and is associated with morphological changes...

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Detalhes bibliográficos
Main Authors: Kazmierczak, B. I., Engel, J. N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127837/
https://ncbi.nlm.nih.gov/pubmed/11895987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.4.2198-2205.2002
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