Role of Gab1 in UV-Induced c-Jun NH(2)-Terminal Kinase Activation and Cell Apoptosis

Exposure of mammalian cells to UV irradiation leads to activation of the c-Jun NH(2)-terminal protein kinase (JNK) pathway, which is associated with cell apoptosis. However, the molecular mechanism for JNK activation by UV exposure is not fully understood. We show here an essential role of a multisu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sun, Yingqing, Yuan, Jing, Liu, Houqi, Shi, Zhongqing, Baker, Kelly, Vuori, Kristiina, Wu, Jie, Feng, Gen-Sheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC344197/
https://ncbi.nlm.nih.gov/pubmed/14749370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.4.1531-1539.2004
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