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Role of Gab1 in UV-Induced c-Jun NH(2)-Terminal Kinase Activation and Cell Apoptosis

Exposure of mammalian cells to UV irradiation leads to activation of the c-Jun NH(2)-terminal protein kinase (JNK) pathway, which is associated with cell apoptosis. However, the molecular mechanism for JNK activation by UV exposure is not fully understood. We show here an essential role of a multisu...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Sun, Yingqing, Yuan, Jing, Liu, Houqi, Shi, Zhongqing, Baker, Kelly, Vuori, Kristiina, Wu, Jie, Feng, Gen-Sheng
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344197/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14749370/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.4.1531-1539.2004
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