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Hepcidin Regulation by BMP Signaling in Macrophages Is Lipopolysaccharide Dependent

Hepcidin is an antimicrobial peptide, which also negatively regulates iron in circulation by controlling iron absorption from dietary sources and iron release from macrophages. Hepcidin is synthesized mainly in the liver, where hepcidin is regulated by iron loading, inflammation and hypoxia. Recentl...

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Detalhes bibliográficos
Main Authors: Wu, Xinggang, Yung, Lai-Ming, Cheng, Wai-Hang, Yu, Paul B., Babitt, Jodie L., Lin, Herbert Y., Xia, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441567/
https://ncbi.nlm.nih.gov/pubmed/23028567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044622
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