A β-hairpin structure in a 13-mer peptide that binds α-bungarotoxin with high affinity and neutralizes its toxicity

Snake-venom α-bungarotoxin is a member of the α-neurotoxin family that binds with very high affinity to the nicotinic acetylcholine receptor (AChR) at the neuromuscular junction. The structure of the complex between α-bungarotoxin and a 13-mer peptide (WRYYESSLEPYPD) that binds the toxin with high a...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Scherf, Tali, Kasher, Roni, Balass, Moshe, Fridkin, Mati, Fuchs, Sara, Katchalski-Katzir, Ephraim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11381118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.111164298
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