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The α-bungarotoxin binding site on the nicotinic acetylcholine receptor: Analysis using a phage–epitope library

The nicotinic acetylcholine receptor (AcChoR) is a ligand-gated ion channel that is activated upon binding of acetylcholine. α-Neurotoxins, in particular α-bungarotoxin (α-BTX), bind specifically and with high affinity to the AcChoR and compete with binding of the natural ligand. We employed a 15-me...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Balass, Moshe, Katchalski-Katzir, Ephraim, Fuchs, Sara
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9177167/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.12.6054
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