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Identification of a hexapeptide that mimics a conformation-dependent binding site of acetylcholine receptor by use of a phage-epitope library.

Monoclonal antibody (mAb) 5.5 is directed against the ligand-binding site of the nicotinic acetylcholine receptor. The epitope for this antibody is conformation-dependent, and the antibody does not react with synthetic peptides derived from the receptor sequence. We have identified a ligand peptide...

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Main Authors: Balass, M, Heldman, Y, Cabilly, S, Givol, D, Katchalski-Katzir, E, Fuchs, S
Formato: Artigo
Idioma:Inglês
Publicado: 1993
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC47832/
https://ncbi.nlm.nih.gov/pubmed/7504273
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