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A β-hairpin structure in a 13-mer peptide that binds α-bungarotoxin with high affinity and neutralizes its toxicity

Snake-venom α-bungarotoxin is a member of the α-neurotoxin family that binds with very high affinity to the nicotinic acetylcholine receptor (AChR) at the neuromuscular junction. The structure of the complex between α-bungarotoxin and a 13-mer peptide (WRYYESSLEPYPD) that binds the toxin with high a...

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Detalhes bibliográficos
Main Authors: Scherf, Tali, Kasher, Roni, Balass, Moshe, Fridkin, Mati, Fuchs, Sara, Katchalski-Katzir, Ephraim
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC34404/
https://ncbi.nlm.nih.gov/pubmed/11381118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111164298
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