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A β-hairpin structure in a 13-mer peptide that binds α-bungarotoxin with high affinity and neutralizes its toxicity

Snake-venom α-bungarotoxin is a member of the α-neurotoxin family that binds with very high affinity to the nicotinic acetylcholine receptor (AChR) at the neuromuscular junction. The structure of the complex between α-bungarotoxin and a 13-mer peptide (WRYYESSLEPYPD) that binds the toxin with high a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Scherf, Tali, Kasher, Roni, Balass, Moshe, Fridkin, Mati, Fuchs, Sara, Katchalski-Katzir, Ephraim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC34404/
https://ncbi.nlm.nih.gov/pubmed/11381118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111164298
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