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Profiling Environmental Chemicals for Activity in the Antioxidant Response Element Signaling Pathway Using a High Throughput Screening Approach

Background: Oxidative stress has been implicated in the pathogenesis of a variety of diseases ranging from cancer to neurodegeneration, highlighting the need to identify chemicals that can induce this effect. The antioxidant response element (ARE) signaling pathway plays an important role in the ame...

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書誌詳細
主要な著者: Shukla, Sunita J, Huang, Ruili, Simmons, Steven O, Tice, Raymond R, Witt, Kristine L, VanLeer, Danielle, Ramabhadran, Ram, Austin, Christopher P, Xia, Menghang
フォーマット: Artigo
言語:Inglês
出版事項: National Institute of Environmental Health Sciences 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440086/
https://ncbi.nlm.nih.gov/pubmed/22551509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1104709
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