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Profiling Environmental Chemicals for Activity in the Antioxidant Response Element Signaling Pathway Using a High Throughput Screening Approach

Background: Oxidative stress has been implicated in the pathogenesis of a variety of diseases ranging from cancer to neurodegeneration, highlighting the need to identify chemicals that can induce this effect. The antioxidant response element (ARE) signaling pathway plays an important role in the ame...

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Detalhes bibliográficos
Main Authors: Shukla, Sunita J, Huang, Ruili, Simmons, Steven O, Tice, Raymond R, Witt, Kristine L, VanLeer, Danielle, Ramabhadran, Ram, Austin, Christopher P, Xia, Menghang
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440086/
https://ncbi.nlm.nih.gov/pubmed/22551509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1104709
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