SNAREpin Assembly by Munc18-1 Requires Previous Vesicle Docking by Synaptotagmin 1

Regulated exocytosis requires the general membrane fusion machinery–soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) and Sec1/Munc18 (SM) proteins. Using reconstituted giant unilamellar vesicles containing preassembled t-SNARE proteins (syntaxin 1·SNAP-25), we determined...

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Main Authors: Parisotto, Daniel, Malsam, Jörg, Scheutzow, Andrea, Krause, Jean Michel, Söllner, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Membrane Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438936/
https://ncbi.nlm.nih.gov/pubmed/22810233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.386805
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