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Resolving the Function of Distinct Munc18-1/SNARE Protein Interaction Modes in a Reconstituted Membrane Fusion Assay

Sec1p/Munc18 proteins and SNAP receptors (SNAREs) are key components of the intracellular membrane fusion machinery. Compartment-specific v-SNAREs on a transport vesicle pair with their cognate t-SNAREs on the target membrane and drive lipid bilayer fusion. In a reconstituted assay that dissects the...

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Autori principali: Schollmeier, Yvette, Krause, Jean Michel, Kreye, Susanne, Malsam, Jörg, Söllner, Thomas H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162418/
https://ncbi.nlm.nih.gov/pubmed/21730064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269886
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