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Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion
Munc13-4 is a widely expressed member of the CAPS/Munc13 protein family proposed to function in priming secretory granules for exocytosis. Munc13-4 contains N- and C-terminal C2 domains (C2A and C2B) predicted to bind Ca(2+), but Ca(2+)-dependent regulation of Munc13-4 activity has not been describe...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328385/ https://ncbi.nlm.nih.gov/pubmed/22508512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201109132 |
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