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SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes

Exocytic vesicle fusion requires both the SNARE family of fusion proteins and a closely associated regulatory subunit of the Sec1/Munc18 (SM) family. In principle, SM proteins could act at an early SNARE assembly step to promote vesicle–plasma membrane adhesion or at a late step to overcome the ener...

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Detalhes bibliográficos
Main Authors: Tareste, David, Shen, Jingshi, Melia, Thomas J., Rothman, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268145/
https://ncbi.nlm.nih.gov/pubmed/18268324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712125105
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