SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion

Sec1/Munc18 (SM) proteins activate intracellular membrane fusion through binding to cognate SNAP receptor (SNARE) complexes. The synaptic target membrane SNARE syntaxin 1 contains a highly conserved H(abc) domain, which connects an N-peptide motif to the SNARE core domain and is thought to participa...

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Bibliographic Details
Main Authors: Shen, Jingshi, Rathore, Shailendra S., Khandan, Lavan, Rothman, James E.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911676/
https://ncbi.nlm.nih.gov/pubmed/20603329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201003148
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