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The trans-SNARE-regulating function of Munc18-1 is essential to synaptic exocytosis
The fusion of neurotransmitter-filled synaptic vesicles with the plasma membrane requires two classes of molecules—SNAP receptor (SNARE) and Sec1/Munc18 (SM) protein. Reconstitution studies suggest that the SM protein Munc18-1 promotes the zippering of trans-SNARE complexes and accelerates the kinet...
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| Vydáno v: | Nat Commun |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4668942/ https://ncbi.nlm.nih.gov/pubmed/26572858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9852 |
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