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The N-peptide–binding mode is critical to Munc18-1 function in synaptic exocytosis
Sec1/Munc18 (SM) proteins promote intracellular vesicle fusion by binding to N-ethylmaleimide–sensitive factor attachment protein receptors (SNAREs). A key SNARE-binding mode of SM proteins involves the N-terminal peptide (N-peptide) motif of syntaxin, a SNARE subunit localized to the target membran...
Gardado en:
| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6254354/ https://ncbi.nlm.nih.gov/pubmed/30275014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005254 |
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