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Total Synthesis of (−)-Irciniastatin B and Structural Confirmation via Chemical Conversion to (+)-Irciniastatin A (Psymberin)

[Image: see text] The total synthesis and structural confirmation of the marine sponge cytotoxin (−)-irciniastatin B has been achieved via a unified strategy employing a late-stage, selective deprotection/oxidation sequence that provides access to both (+)-irciniastatin A (psymberin) and (−)-ircinia...

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Xehetasun bibliografikoak
Egile Nagusiak: An, Chihui, Hoye, Adam T., Smith, Amos B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438514/
https://ncbi.nlm.nih.gov/pubmed/22892009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301783p
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