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Total Synthesis of (−)-Irciniastatin B and Structural Confirmation via Chemical Conversion to (+)-Irciniastatin A (Psymberin)
[Image: see text] The total synthesis and structural confirmation of the marine sponge cytotoxin (−)-irciniastatin B has been achieved via a unified strategy employing a late-stage, selective deprotection/oxidation sequence that provides access to both (+)-irciniastatin A (psymberin) and (−)-ircinia...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3438514/ https://ncbi.nlm.nih.gov/pubmed/22892009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301783p |
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