Investigating the involvement of the ATF6α pathway of the unfolded protein response in adipogenesis

The unfolded protein response (UPR) is activated by endoplasmic reticulum stress resulting from an accumulation of unfolded or mis-folded proteins. The UPR is divided into three arms, involving the activation of ATF-6, PERK and IRE-1, that together act to restrict new protein synthesis and increase...

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Bibliographic Details
Main Authors: Lowe, C E, Dennis, R J, Obi, U, O'Rahilly, S, Rochford, J J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
Subjects:
Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438469/
https://ncbi.nlm.nih.gov/pubmed/22124452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2011.233
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