Prolyl isomerase Pin1 down-regulates tumor suppressor RUNX3 in breast cancer

Emerging evidence demonstrates that RUNX3 is a tumor suppressor in breast cancer. Inactivation of RUNX3 in mice results in spontaneous mammary gland tumors, and decreased or silenced expression of RUNX3 is frequently found in breast cancer cell lines and human breast cancer samples. However, the und...

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Главные авторы: Tsang, Ying-Hung Nicole, Wu, Xue-Wei, Lim, Jing-Shan, Ong, Chee Wee, Salto-Tellez, Manuel, Ito, Kosei, Ito, Yoshiaki, Chen, Lin-Feng
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438320/
https://ncbi.nlm.nih.gov/pubmed/22580604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.178
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