Prolyl isomerase Pin1 down-regulates tumor suppressor RUNX3 in breast cancer

Emerging evidence demonstrates that RUNX3 is a tumor suppressor in breast cancer. Inactivation of RUNX3 in mice results in spontaneous mammary gland tumors, and decreased or silenced expression of RUNX3 is frequently found in breast cancer cell lines and human breast cancer samples. However, the und...

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Bibliographische Detailangaben
Hauptverfasser: Tsang, Ying-Hung Nicole, Wu, Xue-Wei, Lim, Jing-Shan, Ong, Chee Wee, Salto-Tellez, Manuel, Ito, Kosei, Ito, Yoshiaki, Chen, Lin-Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438320/
https://ncbi.nlm.nih.gov/pubmed/22580604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.178
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