RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α

Transcription factor RUNX3 is inactivated in a number of malignancies, including breast cancer, and is suggested to function as a tumor suppressor. How RUNX3 functions as a tumor supressor in breast cancer remains undefined. Here, we show that about 20% of female Runx3(+/−) mice spontaneously develo...

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Hlavní autoři: Huang, Bo, Qu, Zhaoxia, Ong, Chee Wee, Tsang, Ying-Hung Nicole, Xiao, Gutian, Shapiro, David, Salto-ellez, Manuel, Ito, Kosei, Ito, Yoshiaki, Chen, Lin-Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697905/
https://ncbi.nlm.nih.gov/pubmed/21706051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.252
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