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New insights into the inactivation of gastric tumor suppressor RUNX3: the role of H. pylori infection

Runt-related transcription factor 3, or RUNX3, is a tumor suppressor in gastric cancer. Inactivation of RUNX3 is causally associated with the genesis of gastric cancer, since RUNX3 is frequently inactivated in gastric cancers by hemizygous deletion, hypermethylation of its promoter, or protein mislo...

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Detalhes bibliográficos
Main Authors: Nicole Tsang, Ying-Hung, Lamb, Acacia, Chen, Lin-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909029/
https://ncbi.nlm.nih.gov/pubmed/21268057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22964
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