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New insights into the inactivation of gastric tumor suppressor RUNX3: the role of H. pylori infection

Runt-related transcription factor 3, or RUNX3, is a tumor suppressor in gastric cancer. Inactivation of RUNX3 is causally associated with the genesis of gastric cancer, since RUNX3 is frequently inactivated in gastric cancers by hemizygous deletion, hypermethylation of its promoter, or protein mislo...

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Autors principals: Nicole Tsang, Ying-Hung, Lamb, Acacia, Chen, Lin-Feng
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909029/
https://ncbi.nlm.nih.gov/pubmed/21268057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22964
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