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Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation
Chronic infection with cagA-positive Helicobacter pylori is the strongest risk factor for the development of gastric adenocarcinoma. The cagA gene product CagA is injected into gastric epithelial cells and disturbs cellular functions by physically interacting with and deregulating a variety of cellu...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980823/ https://ncbi.nlm.nih.gov/pubmed/20676134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.304 |
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