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Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation

Chronic infection with cagA-positive Helicobacter pylori is the strongest risk factor for the development of gastric adenocarcinoma. The cagA gene product CagA is injected into gastric epithelial cells and disturbs cellular functions by physically interacting with and deregulating a variety of cellu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tsang, YH, Lamb, A, Romero-Gallo, J, Huang, B, Ito, K, Peek, RM, Ito, Y, Chen, LF
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980823/
https://ncbi.nlm.nih.gov/pubmed/20676134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.304
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